Lyrenol tablet 2023-02-11T09:53:40+00:00

Allylestrenol – 5 mg
Packing: 3 x 10 Alu-Alu

Lyrenol contains allyestrenol. It is a synthetic progestogen which prevents threatened miscarriage, frequent pregnancy loss.

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  • Frequent pregnancy loss
  • Premature labor
  • Threatened miscarriage
  • In men it is used for benign prostate hyperplasia

5mg tid for five days

Structurally and functionally allyestrenol is similar to progesterone. For producing its action the drug binds to estrogen and progesterone receptor present in hypothalamus, pituitary and female reproductive tract. After binding to the target receptor it will slow the release of GnHR (gonadotropin releasing hormone) from hypothylamus. It causes the stimulation of mammary alveolar tissue and also causes relaxation of smooth muscle.

Distribution

The drug is well distributed in the body with half life of 9.46hrs.

Excretion

The drug metabolites are excreted in urine and bile.

  • Undiagnosed vaginal bleeding
  • Hypersensitivity
  • Thrombophleobitis ( inflammation of wall of vein )
  • Hormone dependent carcinoma
  • Severe hepatic impairment
  • Pregnancy
  • Discontinue the drug if causing the vision loss
  • Cardia & Renal dysfunction
  • Epilepsy
  • Migraine
  • Lactation
  • Diabetic patients
  • May cause inability for operating a machinery
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