NORISTA 10 CR 2019-09-27T05:31:44+00:00

Norethisterone – 10 mg (Controlled Release Tablets)
Packing: 3 x 10 Alu-Alu

Norista 10 CR contains norethisterone. It is also called as norethindrone which is a synthetic, orally active progestin which is the acetic acid ester of northindrone.

  • Abnormal uterine bleeding
  • Endometriosis
  • Secondary amenorrhea

2.5mg-10mg can be given for 5 to 10 days in the second half of the menstrual cycle.

The drug produce same action as of progestogen. The drug diffuses freely into the target cells and causes binding with progesterone receptors. It mainly causes delay in the onset of the periods and helps in controlling the uterine bleeding. The drug also produces contraceptive effect as it causes negative feedback inhibition of pituitary gonadotropin which causes deterrence of ovulation.


After oral administration the drug is well absorbed from GI tract


The drug highly binds to plasma proteins. About  36% bound to sex hormone-binding globulin and 61% bound to albumin. The metabolism of the drug is through liver with first pass metabolism.


About 50-80% of the drug is excreted through urine and about 40% of the drug is excreted through feces.

  • Undiagnosed uterine bleeding
  • Severe hepatic dysfunction
  • Abnormal metabolism of blood pigment hemoglobin
  • Thromboembolic disease
  • Hypertensive patients
  • Asthmatic patients
  • Patients with renal impairement
  • Migraine type headache
  • Previous depression
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